Contemporary development trends are increasingly pushing cities away from a path of socially just and sustainable development that could offer a decent life to all city-dwellers. Even in cities with a vital economy we are witnessing a dramatic decoupling of economic growth from social development, resulting in all sorts of problems. The model of “the human city” suggests an integrative path in order to move toward that harmonious development of society and economy. The text of The Milan Charter, scientific legacy of Expo Milano 2015, is available at the end of the book.